U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

nasp nuclear autoantigenic sperm protein (histone-binding) [ Danio rerio (zebrafish) ]

Gene ID: 799570, updated on 27-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
naspprovided by ZNC
Official Full Name
nuclear autoantigenic sperm protein (histone-binding)provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5511
See related
Ensembl:ENSDARG00000039208 AllianceGenome:ZFIN:ZDB-GENE-030131-5511
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:56007; zgc:85651; wu:fd20g12
Summary
Predicted to enable histone binding activity. Predicted to be involved in CENP-A containing chromatin assembly and DNA replication-dependent chromatin assembly. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in several structures, including eye; immature eye; pectoral fin; pharyngeal arch; and ventricular zone. Orthologous to human NASP (nuclear autoantigenic sperm protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (33911154..33916796, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (33926464..33932098, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene GC-rich promoter binding protein 1-like 1 Neighboring gene coiled-coil domain containing 17 Neighboring gene aldo-keto reductase family 1, member A1b (aldehyde reductase) Neighboring gene pre-mRNA processing factor 38A

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Differential gene expression and biomarkers in zebrafish (Danio rerio) following exposure to produced water components. Holth TF, et al. Aquat Toxicol, 2008 Dec 11. PMID 18963085
  2. Comparative analysis of single-cell transcriptomics in human and Zebrafish oocytes. Can H, et al. BMC Genomics, 2020 Jul 8. PMID 32640983, Free PMC Article
  3. Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis. Recher G, et al. Development, 2013 Dec. PMID 24198278
  4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC56007, MGC85651

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in CENP-A containing chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in DNA replication-dependent chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
nuclear autoantigenic sperm protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199782.2 → NP_956076.2  nuclear autoantigenic sperm protein

    Status: VALIDATED

    Source sequence(s)
    CR854855, EH441964, EH457062, EH473871, EH482784
    UniProtKB/TrEMBL
    A0A8M1PBV7, F1QNE0
    Related
    ENSDARP00000117697.1, ENSDART00000138488.3
    Conserved Domains (3) summary
    sd00006
    Location:381 → 415
    TPR; TPR repeat [structural motif]
    pfam10516
    Location:386 → 423
    SHNi-TPR; SHNi-TPR
    pfam13424
    Location:385 → 460
    TPR_12; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    33911154..33916796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476951.1 → XP_021332626.1  nuclear autoantigenic sperm protein isoform X1

    UniProtKB/TrEMBL
    A0A8M9QAI4
    Conserved Domains (2) summary
    sd00006
    Location:381 → 415
    TPR; TPR repeat [structural motif]
    cl26511
    Location:106 → 514
    Neuromodulin_N; Gap junction protein N-terminal region

  2. XM_021476952.1 → XP_021332627.1  nuclear autoantigenic sperm protein isoform X2

    UniProtKB/TrEMBL
    A0A8M9PMB8
    Related
    ENSDARP00000117331.1, ENSDART00000137447.2
    Conserved Domains (3) summary
    sd00006
    Location:181 → 215
    TPR; TPR repeat [structural motif]
    pfam10516
    Location:186 → 223
    SHNi-TPR; SHNi-TPR
    cl26250
    Location:180 → 282
    TPR_6; Tetratricopeptide repeat

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395259.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    216467..222069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous